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Nepal Ausadhi Limited

Cetamol 500mg Tab

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PARACETAMOL 500MG Tablet is used to temporarily relieve fever and mild to moderate pain such as muscle ache, headache, toothache, arthritis, and backache. This medicine should be used with caution in patients with liver diseases due to the increased risk of severe adverse effects. 

 

Indications:

  • Relief of mild-to-moderate pain
  • Treatment of fever
  • Unlabeled use(s): Pain and fever prophylaxis after vaccination. 

Dosage:

  • ORAL: ADULTS: PO 325 to 650 mg prn q 4 to 6 hr or 1 g 3 to 4 times/day. Do not exceed 4 g/day. CHILDREN: PO 10 to 15 mg/kg dose prn q 4 to 6 hr; do not exceed 5 doses/24 hr. 
  • SUPPOSITORIES: ADULTS: PR 650 mg q 4 to 6 hr; do not exceed 6 suppositories/24 hr. CHILDREN: 3–6 YR: PR 120 mg q 4 to 6 hr; do not exceed 720 mg/24 hr. CHILDREN: 6–12 YR: PR 325 mg q 4 to 6 hr; do not exceed 2.6 g/24 hr. 

Onset of Action: The pain relieving effect of this medicine can be observed within an hour of administration. For fever reduction, the time taken to show the effect is about 30 minutes.

Duration of Action: The effect of this medicine lasts for an average duration of 46 hours.

 

Side Effects

  • Nausea or Vomiting
  • Allergic skin reaction
  • Gastric / Mouth Ulcer
  • Anemia
  • Fatigue 
  • Unusual bleeding or bruising 

Interactions:

  1. Interaction with Medicines: Severe interaction with sodium nitrite,leflunomide,prilocaine.

 

Contraindications:

  •  Allergy: This medicine is not recommended for use if you have a known allergy to paracetamol or any other components present along with it.
  • Analgesic Nephropathy (Kidney Disease): This medicine is not recommended for use in patients suffering from kidney diseases associated with the excessive use of painkillers.
  • Severe liver impairment: This medicine is not recommended for use in patients with severe liver diseases due to the increased risk of worsening of the patient's condition.

 

Warnings:

  • Liver Disease: This medicine should be used with extreme caution in patients with liver function impairment or active liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function is necessary while receiving this medicine. Report any symptoms such as nausea, fever, rashes, dark urine, etc. to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
  • Chronic malnutrition: This medicine shall be used with extreme caution in patient suffering from malnutrition due to increased chance of severe side effects. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
  • Pregnancy: This medicine is not recommended for use in pregnant women unless necessary and the potential benefits outweigh the risks involved. This medicine is not known to cause any harm to the fetus, but should only be used after consulting with a doctor. 
  • Lactation: This medicine is safe to use during breastfeeding. However, it is advised to consult your doctor before taking this medicine. Monitoring the infant for any undesired side effects like skin rashes or diarrhea while taking this medicine is advised.
  • Alcoholism: This medicine should be used with extreme caution in patients with chronic alcohol use due to the increased risk of serious liver injuries. Close monitoring of liver function is recommended for such patients. Report any unusual symptoms to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition of the patient. 

General Instructions:

  • Take this medicine as prescribed by a doctor.
  • You may take this medicine with or without food.
  • Donot take in large amounts than advised.
  • Usage should never exceed the recommended daily dose.

Storage Conditions:

  • Store at room temperature, under 77°F (25ºC).
  • Keep it away from high temperatures. 

Substitutes: 

Disclaimer
The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of the physician or other qualified health provider with any question you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.
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