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Aldactone 100mg Tab

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ALDACTONE 100 mg Tablet is a diuretic which is used to control high blood pressure and edema. It is usually taken once daily, preferably in the daytime to prevent sleep disturbances. Frequent monitoring of blood pressure and electrolytes level is necessary.

 

Indications:

  • Primary Hyperaldosteronism
  • Congestive Heart Failure
  • Hypertension
  • Hypokalemia

Dosage:

  • Hypertension: 25-100mg PO qDay or divided q12hr initially; may adjust dosage to patient response q2weeks.
  • Edema: 100 mg qDay or divided q12hr for 5 days initially; then adjust does based on patient response; range: 25-200 mg PO qDay or divided q12hr
  • Congestive Heart Failure: 25mg/day PO initially if serum potassium ≤5 mEq/L and eGFR >50 mL/min/1.73 m²; if tolerated, may increase to 50 mg/day as clinically indicated; if 25 mg/day not tolerated, reduce frequency to qoD
  • Hypokalemia: 25-100 mg PO qDay
  • Hirsutism (Off-label): 50-200 mg PO qDay or divided q12hr

Onset of Action: The effect of this medicine can be observed in 2 to 4 hours.

Duration of Action: The effect of this medicine lasts for an average duration of 2 to 3 days.

 

Side effects:

  • Stomach pain
  • Dizziness
  • Irregular heartbeat
  • Headache
  • Skin rash
  • Gynecomastia

Interactions:

  1. Interaction with Medicines: Severe to moderate interaction with Metformin, Nonsteroidal anti-inflammatory drugs, Angiotensin converting enzyme inhibitors (ACEI's).

  2. Interaction with Disease: 
    Electrolyte imbalance: This medicine is not recommended in patients with electrolytes imbalance. Electrolytes levels should be corrected before starting the treatment. Monitoring of potassium, sodium and other electrolytes levels is necessary.
    > Impaired kidney function: This medicine is not recommended in patients with the kidney disease. The kidney function should be assessd before starting the treatment. Any signs of increase in the potassium levels should be informed to the doctor.

  3. Interactions with Foods: Information not available.

 

Contraindications

  • Allergy
  • Anuria

Warnings:

  • Potassium supplements: This medicine will increase the potassium levels in the blood. Therefore, it is advised to avoid potassium-rich foods (potatoes, banana) and medicines that can increase the potassium levels (ACE inhibitors and potassium supplements).
  • Diabetes: This medicine is not recommended in patients with diabetes due to increase in the potassium levels and increases the risk of irregular heart rhythm.
  • Pregnancy: This medicine is not recommended for pregnant women unless necessary. The benefits and risks should be discussed with the doctor before taking this medicine.
  • Lactation: This medicine is recommended in pregnant women only if necessary. The benefits and risks should be discussed with the doctor before taking this medicine.
  • Safety with alcohol: Consumption of alcohol is not recommended while you are taking this medicine. It may increase the risk of dizziness and fainting. Avoid performing activities that need mental alertness like operating machinery or driving a vehicle.

General Instructions

  • Take the tablet as advised by your doctor.
  • Do not take in larger amounts than prescribed.
  • Take this medicine at day time to prevent sleep disturbance.
  • Drink adequate amount of water.
  • Monitoring of kidney function and electrolytes level is necessary.
  • This medicine should be used with caution due to the risk of dizziness.

Storage Conditions:

  • Store at room temperature, under 77°F (25ºC).
  • Keep it away from high temperatures.

Substitutes:

  • ALDACE 100MG TAB
  • SPIROLAC 100MG TAB
  • ROSETONE 100MG TAB
  • SPILAC 100MG TAB 
  • SPRIL 100MG TAB
Disclaimer
The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of the physician or other qualified health provider with any question you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.
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