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Magnus Pharmaceuticals

Mozart-am (5+50)mg Tab

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MOZART-AM  Tablet is the combination of Losartan (50mg) and Amlodipine (5mg), used in the treatment of high blood pressure and other heart complications. You are advised to take this medicine with a proper diet and regular exercise regimen for an optimal control of the blood pressure.

 

Indications:

  • Treatment of hypertension

Dosage:

  • 1 tablet a day.
  • If the dose is missed, the missed dose should be taken as soon possible. It is advisable to skip the missed dose if it's already time for your next scheduled dose.
  • If overdose, seek emergency medical treatment or contact the doctor in case of overdose.
  • Dose adjustment advised in renal impairment, titrate slowly if CrCl ≤ 10 ml/min and in case of mild to moderate hepatic impairment.

Onset of Action: The peak effect of this medicine can be observed in 1 to 1.5 hours.

Duration of Action: This medicine is excreted largely in faeces and the effect lasts for a duration of approximately 24 hours.

 

Side Effects:

  • Stomach pain
  • Chills
  • Difficulty or painful urination
  • Fast heartbeat
  • Back pain
  • Chest tightness
  • Dizziness
  • Weakness in arms, hands, legs or feet
  • Nasal congestion
  • Sore throat
  • Acid or sour stomach
  • Heartburn

Interactions:

  1. Interaction with Medicines:
    Lithium: Plasma concentrations may be increased by losartan, resulting in an increase in the pharmacologic and adverse effects of lithium.
    Aliskiren: Coadministration of aliskiren and this medicine is not recommended due to the increased risk of serious adverse effects. This risk is especially higher in the elderly population and in patients with diabetes and kidney diseases.
     
  2. Interaction with Diseases:
    Congestive heart failure: This medicine should be used with extreme caution in patients with congestive heart failure due to the increased risk of renal impairment and worsening of the patient's condition.

Contraindications:

  • Allergy: This medicine is not recommended for use in patients with a known allergy to losartan or any other angiotensin receptor blocker or amlodipine.
  • Hyperkalemia
  • Congestive heart failure

Warnings:

  • Pregnancy: This medicine is not recommended for use in pregnant women except in lifethreatening conditions. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.
  • Lactation: This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition
  • Hypotension: Symptomatic hypotension may occur in patients with volume depletion or patients who are treated with high-dose diuretics. It is advised to correct this condition before initiating treatment with this medicine or start the treatment at the lowest effective dose.
  • Hyperkalemia: This medicine may increase the potassium levels in the blood (hyperkalemia). This may cause serious side effects such as fatal cardiac rhythm irregularities. It is advised to avoid potassium-rich foods (potatoes, bananas) and other medicines that may increase potassium levels (ACE inhibitors and potassium supplements) during treatment with this medicine.
  • Impaired liver function: The medicine is not recommended for use in patients with severe hepatic failure.
  • Pediatric population: The safety and efficacy of medicine have not been established in children aged below 6 years. This medicine is not recommended for use in children with GFR less than 30 ml/min.

General Instructions:

  • Take tablet with or without food.
  • Do not take in larger amounts than advised.
  • Inform the doctor if you experience any undesirable effects.

Storage Conditions:

  • Store at room temperature, under 77°F (25ºC).
  • Keep it away from high temperatures.

Substitutes:

Disclaimer
The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of the physician or other qualified health provider with any question you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.
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