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Sanofi Aventis

Lantus 100iu/ml Cartridge (3ml)

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NPR. 1025.33
NPR. 922.8
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Lantus Cartridge is a long-acting analog of insulin used for the treatment of diabetes mellitus. This medicine helps in the utilization of glucose and controlling blood glucose levels in diabetic patients. Patients are advised to follow a strict exercise and diet regimen along with this medicine to get the best possible effect.

 

Indications:

  • Type I Diabetes Mellitus
  • Type II Diabetes Mellitus

Dosage:

  •  SC once daily at bedtime, dose determined by close monitoring under medical supervision.

Onset of Action: The effect of this medicine can be observed within 30 to 90 minutes of administration of the dose.

Duration of Action: The effect of this medicine lasts for an average duration of 24 hours.

 

Side effects:

  • Decreased blood glucose levels
  • Headache
  • Pain at the injection site
  • Sore throat
  • Dizziness and Drowsiness
  • Pale skin
  • Shakiness

Interactions:

  1. Interaction with Medicines: Severe to moderate interaction with Corticosteroids, ACE inhibitors, Gatifloxacin, Aspirin.

  2. Interaction with Diseases: 
    Renal Disease: This medicine should be used with caution in patients with a history of kidney diseases due to the increased risk of severe adverse effects. Close monitoring of blood glucose levels is recommended for such patients. Appropriate dose adjustments may be necessary based on the clinical condition of the patient.
    >Hypokalemia: Caution is advised if this medicine is used in patients at an increased risk of developing hypokalemia or patients suffering from hypokalemia (decreased blood potassium levels) since it may worsen the patient's condition. Close monitoring of clinical condition, appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition of the patient.
    Liver Disease: This medicine should be used with caution in patients with a history of liver diseases due to the increased risk of severe adverse effects. Close monitoring of blood glucose levels is recommended for such patients. Appropriate dose adjustments may be necessary based on the clinical condition of the patient.

 

Contraindications: 

  • Allergy
  • Hypoglycemia

Warnings:

  • Diabetic Ketoacidosis: The formulation is not recommended for the treatment of diabetic ketoacidosis due to the delayed onset of action. Alternative treatment options should be considered based on the clinical condition of the patient.
  • Subcutaneous use only: This medicine is meant for subcutaneous administration only. The long duration of action of this medicine is dependent on a subcutaneous administration. It should not be administered intravenously or intramuscularly.
  • Hypersensitivity reactions: This medicine may cause serious and occasionally fatal hypersensitivity reactions (severe allergic reactions) including anaphylactic shock in some patients. Seek immediate medical intervention if any signs and symptoms of an allergic reaction such as skin rash, sore throat, difficulty breathing, swelling of the face, etc. occur.
  • Hypoglycemia: This medicine may cause hypoglycemia (low blood glucose levels) in some patients. This risk is especially higher in patients suffering from kidney diseases, malnourishment, pituitary gland diseases, etc. Close monitoring of blood glucose levels is recommended for such patients. Appropriate dose adjustments may be required based on the clinical condition. Your doctor may advise you to carry a sugar candy to counteract the effects of low blood sugar levels (hypoglycemia).
  • Hypokalemia (Decreased potassium levels): This medicine should be used with caution in patients at risk of developing hypokalemia or patients suffering from hypokalemia since it may worsen the patient's condition. Close monitoring of potassium levels, appropriate corrective measures, or dose adjustments may be required based on the clinical condition of the patient.
  • Use with other insulins: This medicine should not be diluted or mixed with any other insulin or solution since it may reduce the effects of other insulins if they are administered together.
  • Use in children: 100 IU/ml formulations are not recommended for use in patients less than 6 years of age. 300 IU/ml formulations are not recommended for use in patients less than 18 years of age.
  • Pregnancy: This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving/using this medicine.
  • Breast-feeding: Use of insulin by breastfeeding women is considered acceptable. Breastfeeding women generally require lower doses of insulin.
  • Safety with alcohol: Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of both hypoglycemia (low blood glucose levels) and hyperglycemia (high blood glucose levels) depending on the quantity and frequency of alcohol consumption.

General instructions: 

  • Carefully follow all the instructions given by your doctor.
  • Do not administer in larger or smaller amounts than advised/prescribed.
  • Consult the doctor if you experience any undesirable side effects.
  • Do not stop the use of this medicine without consulting your doctor.
  • Close monitoring of blood glucose levels and frequent follow-up visits with the doctor may be required based on the clinical condition.
  • Never share an injection pen, cartridge, or syringe with another person, even if the needle has been changed.

Storage conditions:

  • Store it in refrigerator (2°C - 8°C).
  • Do not freeze.
  • Do not expose to extreme temperature or direct sunlight.

Substitutes:

Disclaimer
The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of the physician or other qualified health provider with any question you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.
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